While there are plenty of models of .45 caliber pistols, there are a couple (one main one really) that stand out among the rest. We know, that you know, what the obvious one is here, but besides the Colt 1911, and other 1911 models, there is also the Glock 21 and the Smith & Wesson M&P45.
.45 1911 Pistols
While the most obvious and iconic model of .45 pistol is the Colt 1911 due to its reliability proven over a century, slim grip, crispy trigger and massive aftermarket support, many other 1911 clones are also on the market. I like to call the Colt 1911 the Mustang of handguns, but there are also great options like Kimber 1911 if you want an affordable option, or the Springfield Armory 1911.
Glock 21 .45 Caliber
The Glock 21 is a reliable option for .45 pistols due to their polymer design. They also offer a higher capacity than most other .45 caliber pistols, and since they have a Glock build the maintenance is very simple. These are often used by law enforcement and civilian shooters.
Smith & Wesson M&P45
The Smith & Wesson M&P45 is a modern take on a 45 caliber pistol with the ability to add sights, and pic rails underneath for other attachments like a flashlight. The modern ergonomic grip makes it very comfortable to hold and has a strong reputation of reliability and accuracy making the Smith & Wesson M&P45 a favorite among competition shooters.